Re-Irradiation of Progressive or Recurrent DIPG

Titre officiel

ReRAD: A Phase II Canadian Pediatric Brain Tumour Consortium Study of Re-Irradiation as Treatment of Progressive or Recurrent Diffuse Intrinsic Pontine Glioma

Sommaire:

Il s’agit d’une étude à groupe unique à répartition non aléatoire sur une seconde radiothérapie d’un gliome pontique intrinsèque diffus (DIPG).

Description de l'essai

Primary Outcome:

• second progression-free survival

Secondary Outcome:

• overall survival

Study therapy will consist of radiation therapy (RT) given over 17 treatment days (for 30.6 Gy in fractions of 1.8 Gy) or 20 treatment days (for 36 Gy in 1.8 Gy fractions), depending on the time from completion of the first course of RT. Treatment days will generally be weekdays, not including statutory holidays.

Voir cet essai sur ClinicalTrials.gov